The study points to a key role for the neuromodulator serotonin in switching sociability on and off. Normally, Malenka says, sociability depends on release of serotonin in an area deep in the brain ...

In a study published in Science Advances, University of Alabama at Birmingham researchers led by Kasey Brida and Jeremy Day, Ph.D., report that the secreted glycoprotein reelin is a marker for those ...

A new study has found that prolonged nerve injury (in an experimental model of chronic pain) reduces the expression of the transcription factor, Myocyte Enhancer Factor 2C (MEF2C) in the nucleus ...

Reward-seeking and threat avoidance are critical for survival. Pursuing enjoyable things triggers the release of dopamine in the brain, making people feel pleasure. On the contrary, people ...

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine stand out as the most dangerous.

A small device that detects food craving-related brain activity in a key brain region, and responds by electrically stimulating that region, has shown promise in a pilot clinical trial in two patients ...