In the study of bacteria, a longstanding dogma has held that two molecular machines—RNA polymerase, which leads the way in ...

Accurate RNA splicing is essential for gene expression and human health, yet predicting how DNA sequence variations affect ...

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and a process fundamental to all life. But the inner workings of this ...

A DNA-guided CRISPR platform could make RNA detection and control more stable, scalable, and precise, opening new routes for diagnostics, transcriptome engineering, and future therapeutic research.

As published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage over existing CRISPR ...

Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human ...

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

Researchers from the University of Osaka have demonstrated that mitochondrial hyperfusion, when induced by low levels of DRP1 ...