Every time a cell copies its DNA, parts of the genome are exposed and vulnerable to damage or errors. Molecular biologist ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment has been the focus of a 30-year research question. New work from the Crick ...

If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

Faithful replication of the genome is essential for development, tissue homeostasis and prevention of malignancy. Key steps in eukaryotic DNA replication include the licensing of replication origins, ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like ...

As recently as the mid-20th century, aging was described by Nobel Prize laureate Peter Medawar as "an unsolved problem in biology." Today, scientists can analyze the activity of thousands of genes in ...

Tiny, quivering spheres designed to feed and multiply raise prospect of artificial organisms to make drugs, food and fuel ...

Mary-Dell Chilton, Ph.D., an American pioneer in plant sciences known as the “Queen of the Agrobacterium,” died on June 24, ...

Scientists find Arctic microbes swap DNA far more often than expected, offering new clues about climate change and carbon storage.