The serine 31 (Ser31) phosphorylation modification (H3.3S31ph) in the N-terminal tail of the histone variant H3.3 can transform H3.3 nucleosomes from a stable state to a dynamically activated ...

Schematic diagram illustrating the novel epigenetic pathway. The dual modification on histone variant H3.3 recruits CBX7, which brings the scaffold protein KAP1 to chromatin. KAP1 facilitates H3K9me3 ...

A recent review by Prof. Zhu Bing and Associate Professor Xiong Jun from the Institute of Biophysics of the Chinese Academy of Sciences reveals how epigenetic regulation not only maintains gene ...

Neurological disorders represent a growing global health challenge, yet the molecular mechanisms underlying their onset and progression remain incompletely ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...

If the genome is the blueprint of life, epigenetics is the control system that determines when, where, and how genes are expressed. By revealing how chemical modifications to DNA and chromatin shape ...

Image Caption: Epigenetic regulation of receptors. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular bases of ...

What parents experience before conception and during pregnancy can leave a lasting impact on offspring brain development.