Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a ...

Delve into the field of PARP inhibitors, a class that has gained traction in ovarian, breast, and prostate cancers.

Cars patched up after a wreck may look fixed—but never run quite as before. The same may hold true for chromatin, according to a study published in Science on November 6. In response to double-strand ...

A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or stop disease progression. Research has identified a critical DNA repair ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by researchers at Goethe University Frankfurt, part of the Rhine-Main University ...

Scientists now recognize that spontaneous DNA errors, which we acquire in early development all the way until our last breath ...

A diagram of the DRT3 system, showing Drt3a in yellow and Drt3b in blue. (Hyunbin Lee) Scientists have just discovered an ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...